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Estudios han demostrado que puede contrarrestar los efectos deletéreos de un exceso de NO en los modelos de inflamación crónica

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Although CKD patients demonstrate an impairment in tissue uptake of B12 resulting in functional deficiency [71], the current evidence remains unclear to consider altered B12, folate and elevated tHcy levels as markers for CVD and cardiovascular mortality risk in ESRD and CKD individuals [72]