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Pathways of acetaminophen (APAP) metabolism. APAP‐glucuronide... | Download Scientific Diagram

AST-treated mice showed enhanced expression of liver cholesterol metabolism genes (LDL receptor, 3-hydroxy-3-methylglutaryl-CoA reductase, and sterol regulatory element-binding protein) and β-oxidation-related genes (carnitine palmitoyltransferase-1 and acyl-CoA), but no significant changes in lipogenic gene expression [96]

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The Kaplan-Meier survival curves for the two study groups were superimposable [59]