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Patients with Iron Deficiency and Heart Failure The safety of Injectafer was evaluated in adult patients with iron deficiency and heart failure in randomized controlled trials FAIR-HF (NCT00520780), CONFIRM-HF (NCT01453608) and AFFIRM-AHF (NCT02937454) in which 1016 patients received Injectafer versus 857 received placebo

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NNMT is upregulated in adipose tissue in obesity, and its inhibition is studied as a potential strategy to modulate NAD+ metabolism and metabolic gene expression