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In the context of aging, the degradation of these clusters disrupts the electron transport chain (ETC), particularly at Complex I, leading to electron leakage and subsequent mitochondrial bioenergetic failure 25,26

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The recommended daily intake for adults varies depending on age and gender: 35 mg for men and 25 mg for women aged 50 years or younger, and 30 mg and 20 mg, respectively for older men and women ( Chromium deficiency may present as peripheral neuropathy, insulin resistance, and weight loss