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Protocols and Dosage Regardless of the technique used, standard dosing protocols for adenosine generally remain the same: – First dose: 6 mg – Second dose (if necessary): 12 mg – Third dose (if necessary): 12 mg Some centers use an increasing dose protocol (3 mg, 6 mg, 12 mg) for patients at high risk of side effects

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Sikiric et al., 2010