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On a final note, a novel and attractive dual-targeting approach is represented by the combination of CB 1 R antagonists and CB 2 R agonists, as evidenced by the synergy shown by coadministration of AM6545 and AM1241 for treating diabetic nephropathy (Barutta et al., 2017)
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During the development of cervical cancer related to HPV infection, the HPV genome is integrated through the host genome and HPV has a full life cycle that persists in the host cell
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