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Genotoxic stress triggers Scd6-dependent regulation of translation to modulate the DNA damage response | EMBO Reports | Springer Nature Link

We show that neuroendocrine prostate tumour cells have increased levels of histone H3 lysine 36 dimethylation (H3K36me2), which is catalysed by NSD2 (also known as MMSET or WHSC1) 15,16

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Oxidative stress is the imbalance between the production rate of reactive oxygen and nitrogen species by cell metabolism and the state of the antioxidant machinery, leading to oxidative damage to main biomolecules, including DNA (e.g., Sies et al