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A Phase 2 trial (Obesity Research, 2004) found 12 weeks of subcutaneous AOD-9604 produced statistically significant abdominal fat reduction versus placebo without altering fasting glucose or insulin levels

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A toxicity study in rats administered oral GABA (500-2500 mg/kg/day) for 13 weeks and found no significant abnormalities in behavior, weight gain, or blood indices including general chemistries, glucose, renal function, hematology and liver function