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Furthermore, this creates a vicious cycle, as pro-inflammatory cytokines (e.g., IL-6, TNF-α) are released in response to DAMPs, perpetuating the inflammatory process [22,25,26,27,28,29,30]

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By addressing appetite, fullness, insulin regulation, and food reward at the same time, CagriSema could make weight loss more sustainable, predictable, and psychologically easier for many patients