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Uneven or patchy skin tone Dull or tired-looking skin Post-breakout marks Those looking for tone-balancing care Normal, combination, or oily skin types Avoid if: You prefer minimal or single-ingredient routines PibuMate Tip Apply consistently to the entire face rather than spot treating

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People with Severe Liver Disease Should Not Use LDN Therapy Most healthcare providers monitor liver function in people taking LDN treatment, in addition to watching for adverse drug interactions and other side effects