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BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione - ScienceDirect
The cyclic lactam bridge provides substantially enhanced potency (approximately 100-1000× compared to α-MSH depending on receptor and assay) and improved resistance to proteolytic degradation, enabling practical research dosing schedules
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