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Both N-acetylcysteine and glutathione (GSH) supplementation ablated the DNA lesions and DNA damage-response pathways in Nrf2(−/−) cells
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With an initial size of ~200 nm at pH 7.4 due to the balanced steric repulsion of PEG shells and hydrophobic interaction of glycyrrhetinic acid (GA), AuNPs@Re-GA disassembles (~30 nm) in the acidic TME as steric repulsion overpowers hydrophobicity
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