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Studies on rats exposed to CCl4 have shown that EGCG exerts protective effects on the liver through its antioxidative actions (reducing MDA levels and increasing GSH), anti-inflammatory effects (lowering levels of inflammatory markers: TNF-α, NF-κB, IL-1β, and TGFβ), and antifibrotic effects (reducing fibrotic markers: p -ERK and p -Smad1/2 protein expression) [87]

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87, 3343–3355 10.1002/jnr.22173 [DOI] [PMC free article] [PubMed] [Google Scholar] Johnson E