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A gentle electrical current helps move that substance away from the electrode and through the skin by mechanisms commonly described as the following: Electromigration: movement of charged molecules in response to an electric field Electro-osmosis: movement of fluid that may help carry molecules through the skin Current-assisted skin permeation: increased transport across the skin barrier during controlled electrical application How NAD+ Iontophoresis Patches Are Intended to Work An NAD⁺ iontophoresis patch is intended to combine an NAD⁺ solution with a wearable iontophoresis delivery system