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MLCK activation by the extracellular signal-regulated kinases 1/2 (ERK1/2) signaling pathways was also related to IL-1 β mediated changes in TJ [21, 22]

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387-392 deletion (Δ 387-392), 1197-1202 deletion (Δ 1197-1202), 1212-1217 (Δ 1212-1217), and 1417-1422 deletion (Δ 1417-1422) were generated using GFP-ZO-1 as templates