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Mitigative Effects on DM Complications (Figure 1D) CGA reduces glomerular hypertrophy and proliferation and mesangial cell expansions, decreases kidney malondialdehyde (MDA) levels, increases antioxidants (such as SOD, CAT, and GSH-Px), and reduces factors associated with oxidation and inflammation (such as IL-6, TNF-α, COX-2, and IL-1β) in the kidney of a diabetic nephropathy rat model [127,128]
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