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Mice were placed onto a cage hopper and infused with semaglutide, GLP-1–MK-801 or vehicle (isotonic saline) over 60 s at a total infusion volume of 2 µl through a Hamilton syringe mounted onto an automated syringe pump (Harvard Apparatus) and a 33-gauge internal cannula (PlasticsOne, C315IS-4/SPC, 2.5 mm)

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In other words, the “1 in 10 people” getting worse after starting with the B12 shots may just be the result of one of the other coexisting illnesses getting worse